| SAFE | State Administration of Foreign Exchange | 国家外汇管理局 |
| SAFE | Student Association for Fire Ecology | 消防生态学学生协会 |
| SAFE | Student Association for Freedom of Expression (MIT) | 学生言论自由协会（MIT） |
| SAFE | Sportsmen's Association for Firearms Education, Inc. (Commack, NY) | 运动员协会有限公司为武器的教育。纽约(Commack |
| SAFE | Space and Flight Equipment Association (now just SAFE Association) | 太空和飞行设备协会（现在只是SAFE协会） |
| SAFE | Student Association for the Environment (Pomona College) | 学生环境协会（波莫纳学院） |
| SAFE | Survival and Flight Equipment Association | 生存和飞行设备协会 |
| SAFE | Standard Archive Format for Europe | 欧洲标准存档格式 |
| SAFE | System for Automated Flight Efficiency | 自动飞行效率系统 |
| SAFE | Signatures and Authentication for Everyone (formerly Secure Access for Everyone) | 每个人的签名和身份验证（以前是每个人的安全访问） |
| SAFE | Security Against Fraud Enhancements (sticker on a bogus card swipe device) | 防欺诈安全增强功能（假刷卡设备上的标签） |
| SAFE | Secure Access for Everyone (now Signatures and Authentication for Everyone) | 每个人的安全访问（现在是每个人的签名和身份验证） |
| SAFE | Stochastic Analysis of Fragmentation Effects | 碎片效应的随机分析 |
| SAFE | Solar Array Flight Experiment | 太阳能阵列飞行实验 |
| SAFE | Silvoarable Agroforestry For Europe | 欧洲可耕种农林 |
| SAFE | Semiconductor Advances for Future Electronics | 面向未来电子的半导体进展 |
| SAFE | State Administration of Foreign Exchange (China) | 国家外汇管理局（中国） |
| SAFE | Socially Accountable Farm Employers | 社会责任农场雇主 |
| SAFE | Skills & Assets for Excellence (police) | 技能和资产(警方) |
| SAFE | Sensor Analysis and Fusion Environment (US Defense Threat Reduction Agency) | 传感器分析与融合环境（美国国防威胁降低局） |
| SAFE | Shaw Air Force Employees (Shaw AFB, SC) | Shaw空军员工（Shaw AFB，SC） |
| SAFE | Structural Appraisal of Fatigue Effects | 疲劳效应的结构评估 |
| SAFE | Smoke Alarms For Escape (Ocala, FL fire safety program) | 逃生烟雾报警器（佛罗里达州奥卡拉消防安全计划） |
| SAFE | Safety Assessment/Facility Evaluation | 安全评估/设备的评价 |
| SAFE | Signal Processing Applications for Public Security and Forensics (IEEE Workshop) | 公共安全和取证的信号处理应用（IEEE研讨会） |
| SAFE | Safety Advancement For Employees | 员工安全促进 |
| SAFE | Secure Access Federal/State Exchange | 联邦国家安全访问交流 |
| SAFE | Safe, Active, Family Environment | 安全、活跃、家庭环境 |
| SAFE | Seniors Against Federal Extravagance | 老年人反对联邦奢侈 |
| SAFE | Safety Analysis and Functional Evaluation (oil & gas) | 安全分析和功能评价(石油和天然气) |
| SAFE | Standard Approach for Evaluators (inspection compliance) | 评估人员标准方法（检查合规性） |
| SAFE | Selected Area For Evasion (combat search and rescue) | 选择的躲避区域（战斗搜救） |
| SAFE | San Andreas Fault Experiment | 圣安德烈亚斯断层实验 |
| SAFE | Strength Agility Flexibility Endurance (four areas of fitness) | 力量敏捷灵活性耐力（四个健身领域） |
| SAFE | Safety Actions for Europe | 欧洲安全行动 |
| SAFE | Security Architecture for Enterprise | 企业安全体系结构 |
| SAFE | Secure Authorized Foreign Employee | 安全授权外籍员工 |
| SAFE | Shores Action Force Eyes (Marion County, Florida) | Shores Action Force Eyes（佛罗里达州马里昂县） |
| SAFE | Secure Architecture for Enterprise | 企业安全体系结构 |
| SAFE | Safety Awareness and Family Education | 安全意识和家庭教育 |
| SAFE | Service Authority for Freeways and Expressways | 高速公路和高速公路服务机构 |
| SAFE | Surgery, Antibiotics, Face Washing and Environmental Improvement (WHO) | 手术、抗生素、洗脸和环境改善（世界卫生组织） |
| SAFE | Self-Abuse Finally Ends (anti-self-injury treatment & support organization) | anti-self-injury自责下去最终结束的治疗和支持组织 |
| SAFE | South Africa, Far East (cable project) | 南非、远东（电缆项目） |
| SAFE | Security, Automatic weapons, Fields of fire, Entrenchment | 安全、自动武器、火力场、嵌入 |
| SAFE | Santa Fe National Historic Trail (US National Park Service) | 圣达菲国家历史步道（美国国家公园管理局） |
| SAFE | Secure Address Foundation Extensions (Meta IP) | 安全地址基础扩展（Meta IP） |
| SAFE | Security And Freedom Enhanced | 安全和自由增强 |
| SAFE | Services to Abused Families, Inc. | 虐待家庭服务公司。 |
| SAFE | Student Advocates for Freedom & Equality | 自由与平等的学生的提倡者 |
| SAFE | Safety Awareness Faith Empowerment | 安全意识信念授权 |
| SAFE | Smoke Alarms for Everyone | 每个人的烟雾报警器 |
| SAFE | Security Awareness For Employees | 员工安全意识 |
| SAFE | Safe And Friendly Environment | 安全友好的环境 |
| SAFE | Security and Freedom through Encryption | 通过加密实现安全和自由 |
| SAFE | Standard Annual Frequency Estimate | 标准年频率估算 |
| SAFE | Sexual Assault Free Environment | 无性侵环境 |
| SAFE | Support for the Analyst's File Environment (US DoD) | 支持分析家的文件的环境(美国国防部) |
| SAFE | Safe, Active, and Family Environment | 安全、活跃和家庭环境 |
| SAFE | Safety Awareness, Faith, and Empowerment | 安全意识、信念和授权 |
| SAFE | Smoke Alarms For Every Home | 每个家庭的烟雾报警器 |
| SAFE | Security and Freedom Ensured Act (related to USA PATRIOT Act) | 安全与自由保障法案（与美国爱国者法案相关） |
| SAFE | Save America's Fossils for Everyone | 对每个人来说都是美国化石保存 |
| SAFE | Student Awareness Of Fire Education | 学生消防教育意识 |
| SAFE | Student and Family Empowerment (drug and violence prevention program) | 学生和家庭赋权（毒品和暴力预防计划） |
| SAFE | Safety Abuse and Fraud Education | 安全滥用和欺诈教育 |
| SAFE | Saving Animals for Everyone | 为每个人拯救动物 |
| SAFE | Sustainable Agriculture, Food and Economics | 可持续农业、食品和经济 |
| SAFE | Student Assistance and Family Empowerment | 学生援助和家庭赋权 |
| SAFE | Stationary Attachment Flexible Endoskeletal (prosthesis) | 固定附件柔性内骨骼（假体） |
| SAFE | Sexual Assault Forensic Examiner | 性侵法医 |
| SAFE | Serena Application Framework for Enterprises | Serena企业应用程序框架 |
| SAFE | Secure, Accessible, Fast, Easy (Paypal) | 安全、可访问、快速、简单（Paypal） |
| SAFE | Survivors and Allies for Education | 幸存者和教育同盟 |
| SAFE | Sudan-American Foundation for Education, Inc | 苏丹美国教育基金会 |
| SAFE | Stop Abuse for Everyone | 停止虐待每个人 |
| SAFE | Security and Accountability for Every (Port Act) | 每个人的安全和责任（港口法） |
| SAFE | Sane Alternatives to the Firearms Epidemic | 枪支流行的Sane替代品 |
| SAFE | Students Against Fees in Education | 学生反对教育收费 |
| SAFE | secure analyst file environment (US DoD) | 安全分析文件环境（美国国防部） |
| SAFE | Safeguards Automated Facility Evaluation (United State Nuclear Regulatory Commission) | 保障设施自动评估（美国核管理委员会） |
| SAFE | Society for the Advancement of Fission Energy | 裂变能促进会 |
| SAFE | Students, Administrators and Faculty for Equality on Campus | 学生、行政人员和校园平等教师 |
| SAFE | Sane Aviation for Everyone, Inc. | Sane Aviation for Everyone公司。 |
| SAFE | Smokefree Air For Everyone | 人人享有无烟空气 |
| SAFE | Spirituality in Action for Family Empowerment (Trinidad & Tobago) | 行动中的灵性家庭权力(特立尼达岛和多巴哥) |
| SAFE | Nickname for HQ USAF Programs Usually Connected With Security | 总部美国空军项目的昵称通常与安全相关 |
| SAFE | Students Are Friendly to Everyone (McKinley Elementary School; Billings, Montana) | 学生对每个人都很友好（麦金莱小学；蒙大拿州比林斯） |
| SAFE | Security And Freedom through Encryption Act of 1999 (US) | 1999年《加密安全与自由法案》（美国） |
| SAFE | Safe Access and Family Empowerment | 安全通道和家庭赋权 |
| SAFE | School Action for Emergencies | 紧急情况学校行动 |
| SAFE | Safety Awareness and Family Education Network (Child Sex Abuse Prevention) | 安全意识和家庭教育网络（防止儿童性虐待） |
| SAFE | Service Authority for Freeway Emergencies (California) | 高速公路紧急情况服务机构（加利福尼亚州） |
| SAFE | Save America's Free Enterprise (NFIB) | 拯救美国的自由企业(NFIB) |
| SAFE | Safety and Fire Education | 安全与消防教育 |
| SAFE | Spatial Aggregate Fielding Evaluation | 空间聚合实地评估 |
| SAFE | Secular Alliance of Freethought and Enlightenment (Louisville, KY) | 自由思想和启蒙的世俗联盟（肯塔基州路易斯维尔） |
| SAFE | Self-Adaptive Flight Experiment | 自适应飞行实验 |
| SAFE | Sequential Analysis for Force Employment | 劳动力就业的序列分析 |
| SAFE | Slow and easy movements, Apply natural buoyancy, Full lung inflation, Extreme Relaxation (how to float) | 缓慢轻松的运动，施加自然浮力，充分的肺充气，极度放松（如何漂浮） |